Duke University is offering advanced imaging techniques to assess the risk of rupture in unruptured brain aneurysms. These imaging options are considered groundbreaking for determining aneurysm stability, according to Dr. Hasan.
Ferumoxytol, an injectable medication traditionally used to treat chronic anemia, has been found by Dr. Hasan and his team to act as a contrast agent with MRI imaging. It helps detect inflammatory cells responsible for aneurysm eruption. “Think of it like a volcano,” said Dr. Hasan, explaining that the presence of many inflammatory cells indicates potential instability.
For patients who cannot use ferumoxytol due to its side effects, High-Resolution Vessel Wall Imaging offers another option. This technique uses gadolinium contrast in MRI scans to identify active changes within the aneurysm wall.
Quantitative Susceptibility Mapping (QSM) is also available at Duke. It detects micro-bleeds in thin areas of the aneurysm wall, signaling possible rupture risk, especially useful for patients experiencing migraines or tension headaches.
Computational Dynamics and Finite Element Analysis are additional methods being employed at Duke. They use MRI technology and computer modeling to measure blood movement through the aneurysm and assess wall strength and elasticity respectively.
Photon-Counting CT is another innovative approach offered at Duke for detecting recurrence after coil embolization treatment without requiring contrast dye injection.
Dr. Hasan’s team is actively involved in research initiatives aiming to advance brain aneurysm care further. These include studying devices that record brain artery activity and exploring aspirin use as a treatment option for unruptured brain aneurysms.
“Duke is unique because we have advanced research protocols,” said Dr. Hasan, emphasizing patient involvement in ongoing research efforts even if it doesn’t provide immediate benefits but could help others in the future.
Dr. Hasan is recognized internationally for his expertise in cerebrovascular care and has treated thousands of brain aneurysms using various innovative techniques including awake surgery.
